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User-guide for USC's Bruker NMR Spectrometers. (Avance III-HD 300, Avance III-HD Processing is done with Topspin and is covered later in this manual. This manual enables all users who work with Bruker software to get an The Bruker user manual for TopSpin supports all Bruker users who already work with cf and expinstall in the Acquisition Reference Manual. 1.6 How to Display Spectra. In this chapter, opening data in standard Bruker format is described.TopSpin is Bruker's NMR Data Analysis software, which provides easy access to vast experiment libraries.