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Surgical antimicrobial prophylaxis is the use of antimicrobials to prevent infections that may occur as a result of a surgical procedure.preoperative surgical antibiotic prophylaxis. 1. Introduction. The benefit of the routine use of antimicrobial prophylaxis prior to non-clean and. Recommendations for selection of antimicrobial agents for specific surgical procedures and alternative agents (e.g., for patients with allergies to β-lactam Four of their 29 recommendations provide instructions on AP to prevent SSIs: antibiotics must be administered between 60 and 120 minutes before the surgery; no
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