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Within umbrella reviews, quantitative or qualitative systematic reviews may be incorporated, as well as meta-analyses of existing research. There are 11 questions to guide the appraisal of systematic reviews or meta-analyses. Each question should be answered as "yes", "no", or "unclear". Not applicable "NA" is also Systematic review A systematic review is a summary of the medical literature that uses explicit and reproducible methods to systematically search, critically appraise, and synthesize on a specific issue. It synthesizes the results of multiple primary studies related to each other by using strategies that reduce biases and random errors. [ 7] A systematic review: Parkinson's disease Josef Finsterer* Department of Clinical Neuroscience, Institute of Psychiatry, Psychology & Neuroscience at King's College London, London, United Kingdom Address for correspondence: Josef Finsterer Department of Clinical Neuroscience, Institute of Psychiatry, Systematic Reviews encompasses all aspects of the design, conduct and reporting of systematic reviews. The journal publishes high quality systematic review products including systematic review protocols, systematic reviews related to a very broad definition of health, rapid reviews, updates of already completed systematic reviews, and methods research related to the science of systematic reviews, such as decision modelling. Module A: Overview of Systematic Reviews Module B: Evaluating Systematic Reviews Module C: Steps for Conducting a Systematic Review o Step 1: Assembling the team o Step 2: Develop the protocol or work plan o Step 3: Question/topic refinement o Step 4: Systematic and comprehensive searches for evidence o Step 5: Inclusion/exclusion rules Family of Systematic Reviews • Qualitative synthesis can be seen as one of several review methods that are part of, or leading to, systematic reviews: -Meta-Analysis (MA) -Qualitative Synthesis -Rapid Evidence Assessments (REA) -Scoping -Level of evidence reviews Each has a unique method of answering research questions
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